Nonulcer Dyspepsia
When all the causes
of epigastric pain have been excluded and there is still
pain, the diagnosis is functional or nonulcer dyspepsia. There is no specific
therapy for nonulcer dyspepsia known
to cure the
disorder. Antacids
of various types
from H2 blockers to liquid antacids to PPIs are tried
until something is found to relieve
the discomfort. The cause
of nonulcer dyspepsia
is unknown.
Treatment of Helicobacter pylori in nonulcer dyspepsia is of equivocal value.
If there is no response to anti-secretory therapy with a PPI, you can try to treat H. Pylori
by adding clarithromycin and amoxicillin. Treating H. Pylori will improve
symptoms in another
10–20% of patients.
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