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Wednesday, December 30, 2015

Nonulcer Dyspepsia

Nonulcer Dyspepsia

When all the causes of epigastric pain have been excluded and there is still pain, the diagnosis is functional or nonulcer dyspepsia. There is no specific therapy for nonulcer dyspepsia known to cure the disorder. Antacids of various types from H2 blockers to liquid antacids to PPIs are tried
until something is found to relieve the discomfort. The cause of nonulcer dyspepsia is unknown.

Treatment of Helicobacter pylori in nonulcer dyspepsia is of equivocal value. If there is no response to anti-secretory therapy with a PPI, you can try to treat H. Pylori by adding clarithromycin and amoxicillin. Treating H. Pylori will improve symptoms in another 10–20% of patients.

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